DENDRIMER-DOXORUBICIN CONJUGATES EXHIBIT IMPROVED ANTICANCER ACTIVITY AND REDUCE DOXORUBICIN-INDUCED CARDIOTOXICITY IN A MURINE HEPATOCELLULAR CARCINOMA MODEL.

Hepatocellular carcinoma (HCC) is the 2nd leading cause of cancer-related deaths every year globally.The most common form of treatment, hepatic arterial infusion (HAI), involves the direct injection of doxorubicin (DOX) into the hepatic artery.It is plagued with limited therapeutic efficacy and the occurrence of severe toxicities (e.g.cardiotoxicit

Background: In the last two years, the COVID-19 pandemic has spread all over the world, affecting millions of people.The same infection can manifest in different clinical conditions, ranging from read more mild situations to severe patient impairment, up to their death.The COVID-19 infection can activate innate and adaptive immune systems and cause

Abstract Globally, there are a growing number of dogs in schools.Research suggests that there are potential Military UAV benefits of interactions between children and dogs in educational contexts, for example in terms of social–emotional, cognitive and physical development.However, there is a lack of research examining the potential challenges an

Changes in the global economic paradigm motivate governments and private companies to implement the innovations of the fourth industrial revolution.The COVID-2019 pandemic also became a powerful catalyst for the digitization of management processes, which forced businesses and governments to look for remote opportunities to continue their professio

Muhammad Zeeshan,1 Jiabin Han,1 Alam Rehman,2 Irfan Ullah,3 Fakhr E Alam Afridi4 1College of Business Administration, Liaoning Technical University, Xingcheng, Liaoning Province, 125105, People’s Republic of China; 2Faculty of Management Sciences, National University of Modern Languages, Islamabad, Pakistan; 3Reading Academy, Nanjing Universi